log in |
Message boards : Science : proterna_vae64lat dataset
Author | Message |
---|---|
There is a new data set floating around: proterna_vae64lat | |
ID: 2303 · Reply Quote | |
Thanks for the info. | |
ID: 2304 · Reply Quote | |
Great news 😠| |
ID: 2306 · Reply Quote | |
More (scientific) information will follow. Waiting with bated breath. | |
ID: 2307 · Reply Quote | |
The Genotype-Tissue Expression (GTEx) project is an ongoing effort to build a public resource of tissue-specific human gene expression. The Enhancing GTEx (eGTEx) project extends the GTEx project to combine gene expression with additional molecular measurements on the same tissues. Within the eGTEx project, protein and RNA expression levels in 32 normal human tissues from 14 individuals were obtained by quantitative mass spectrometry and RNA sequencing, respectively. The original dataset was downloaded from https://www.gtexportal.org/home/datasets. Data on protein and RNA levels for approximately 12000 genes were integrated with an approach based on a variational autoencoder, obtaining a latent representation composed of 64 variables. | |
ID: 2308 · Reply Quote | |
Thanks toma. That sounds like the combinatorials are endless. I'm not familiar with the field of gene expression but things like various skin diseases and osteoporosis come to mind. Are there examples of how eGTEx might lead to new or better diagnostics or treatments? | |
ID: 2309 · Reply Quote | |
I just inserted in the queue 51 genes (51*18 workunits) related to leukemia (see https://omim.org/), to be "expanded" within the proterna_vae64lat dataset. | |
ID: 2312 · Reply Quote | |
I just inserted in the queue 51 genes (51*18 workunits) related to leukemia (see https://omim.org/), to be "expanded" within the proterna_vae64lat dataset. Great!! | |
ID: 2313 · Reply Quote | |
Unfortunately the eGTEx dataset does not currently contain samples from bones or skin, therefore our first analyses will be focused on genes responsible for neurodegenerative diseases and hematologic malignancies. | |
ID: 2314 · Reply Quote | |
Message boards :
Science :
proterna_vae64lat dataset