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1)
Message boards :
Science :
proterna_vae64lat dataset
(Message 2314)
Posted 20 May 2021 by toma Unfortunately the eGTEx dataset does not currently contain samples from bones or skin, therefore our first analyses will be focused on genes responsible for neurodegenerative diseases and hematologic malignancies. |
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2)
Message boards :
Science :
proterna_vae64lat dataset
(Message 2308)
Posted 12 May 2021 by toma The Genotype-Tissue Expression (GTEx) project is an ongoing effort to build a public resource of tissue-specific human gene expression. The Enhancing GTEx (eGTEx) project extends the GTEx project to combine gene expression with additional molecular measurements on the same tissues. Within the eGTEx project, protein and RNA expression levels in 32 normal human tissues from 14 individuals were obtained by quantitative mass spectrometry and RNA sequencing, respectively. The original dataset was downloaded from https://www.gtexportal.org/home/datasets. Data on protein and RNA levels for approximately 12000 genes were integrated with an approach based on a variational autoencoder, obtaining a latent representation composed of 64 variables. |
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3)
Message boards :
Science :
New experiment: gene network expansion of human pathologically relevant genes
(Message 1329)
Posted 6 Jun 2018 by toma The goal of this experiment is the identification of gene networks involving human genes of medical relevance for two broad families of human pathologies: motor neuron diseases (https://en.wikipedia.org/wiki/Motor_neuron_disease) and hematopoietic tumors (https://en.wikipedia.org/wiki/Tumors_of_the_hematopoietic_and_lymphoid_tissues). Human gene network expansion will take advantage of the comprehensive gene expression dataset provided by the FANTOM project (http://fantom.gsc.riken.jp/5/data/). |