Miscellaneous gene-related news
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robertmiles
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Message 2473 - Posted: 24 Jan 2022, 6:09:35 UTC

First sickle cell patient treated with CRISPR gene-editing still thriving

https://www.npr.org/sections/health-shots/2021/12/31/1067400512/first-sickle-cell-patient-treated-with-crispr-gene-editing-still-thriving

robertmiles
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Message 2475 - Posted: 24 Jan 2022, 16:18:11 UTC

Fastest DNA sequencing technique helps undiagnosed patients find answers in mere hours

https://scienceblog.com/527902/fastest-dna-sequencing-technique-helps-undiagnosed-patients-find-answers-in-mere-hours/

robertmiles
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Message 2482 - Posted: 25 Jan 2022, 23:44:34 UTC

Unraveling the complexity of vitamin B12 diseases

https://scienceblog.com/527946/unraveling-the-complexity-of-vitamin-b12-diseases/


Arthritis and microbiota: molecules of bacterial origin exacerbate inflammation

https://scienceblog.com/527953/arthritis-and-microbiota-molecules-of-bacterial-origin-exacerbate-inflammation/

robertmiles
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Message 2485 - Posted: 27 Jan 2022, 6:05:11 UTC

Long-range four-stranded DNA structures found to play a role in rare aging disease

https://scienceblog.com/527122/long-range-four-stranded-dna-structures-found-to-play-a-role-in-rare-aging-disease/

robertmiles
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Message 2486 - Posted: 27 Jan 2022, 21:29:46 UTC

New gene to make plants heat-tolerant in rising temperatures

https://scienceblog.com/524682/new-gene-to-make-plants-heat-tolerant-in-rising-temperatures/


Biologists discover an ‘evening’ protein complex that regulates plant growth

https://scienceblog.com/46251/biologists-discover-an-evening-protein-complex-that-regulates-plant-growth/


Sequencing the Condor Genome for Insights into Human Diversity

https://scienceblog.com/524739/sequencing-the-condor-genome-for-insights-into-human-diversity/


How the malaria parasite defends itself against fever

https://scienceblog.com/524882/how-the-malaria-parasite-defends-itself-against-fever/

robertmiles
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Message 2487 - Posted: 28 Jan 2022, 5:36:13 UTC

Dry season parasite behaviour could provide new route for malaria treatment

https://horizon.scienceblog.com/1784/dry-season-parasite-behaviour-could-provide-new-route-for-malaria-treatment/


Drug-Bacteria Found In The Guts Of Lemurs Who Live Around Humans

https://scienceblog.com/524671/drug-resistant-bacteria-found-in-the-guts-of-lemurs-who-live-around-humans/


Machine learning discovers new sequences to boost drug delivery

https://scienceblog.com/524690/machine-learning-discovers-new-sequences-to-boost-drug-delivery/


New Blood: Lab-Grown Stem Cells Bode Well for Transplants, Aging Research

https://scienceblog.com/524746/new-blood-lab-grown-stem-cells-bode-well-for-transplants-aging-research/

Jim1348
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Message 2488 - Posted: 29 Jan 2022, 7:55:27 UTC

What If (Almost) Every Gene Affects (Almost) Everything?

But Evan Boyle, Yang Li, and Jonathan Pritchard from Stanford University think that this framework doesn’t go far enough.

They note that researchers often assume that those thousands of weakly-acting genetic variants will all cluster together in relevant genes. For example, you might expect that height-associated variants will affect genes that control the growth of bones. Similarly, schizophrenia-associated variants might affect genes that are involved in the nervous system. “There’s been this notion that for every gene that’s involved in a trait, there’d be a story connecting that gene to the trait,” says Pritchard. And he thinks that’s only partly true.

Yes, he says, there will be “core genes” that follow this pattern. They will affect traits in ways that make biological sense. But genes don’t work in isolation. They influence each other in large networks, so that “if a variant changes any one gene, it could change an entire gene network,” says Boyle. He believes that these networks are so thoroughly interconnected that every gene is just a few degrees of separation away from every other. Which means that changes in basically any gene will ripple inwards to affect the core genes for a particular trait.

The Stanford trio call this the “omnigenic model.” In the simplest terms, they’re saying that most genes matter for most things.

https://getpocket.com/explore/item/what-if-almost-every-gene-affects-almost-everything

robertmiles
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Message 2497 - Posted: 31 Jan 2022, 5:51:20 UTC

Gene discoveries give new hope to people who stutter

https://scienceblog.com/527044/gene-discoveries-give-new-hope-to-people-who-stutter/


Gene-editing used to create single sex mice litters

https://scienceblog.com/527051/gene-editing-used-to-create-single-sex-mice-litters/

robertmiles
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Message 2498 - Posted: 1 Feb 2022, 5:52:11 UTC

Microbes help hibernating animals recycle nutrients, maintain muscle through winter

https://scienceblog.com/528025/microbes-help-hibernating-animals-recycle-nutrients-maintain-muscle-through-winter/


Animal welfare belongs at heart of gene editing discussion

https://scienceblog.com/527016/animal-welfare-belongs-at-heart-of-gene-editing-discussion/

robertmiles
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Message 2499 - Posted: 1 Feb 2022, 5:53:40 UTC

How a Rare Brain Mutation Spread Across America

https://www.msn.com/en-us/money/realestate/how-a-rare-brain-mutation-spread-across-america/ar-AAT54TM?ocid=winp1taskbar

robertmiles
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Message 2500 - Posted: 2 Feb 2022, 16:02:46 UTC

Scientists find genetic marker carried by Robert the Bruce's relatives

https://www.msn.com/en-us/news/world/scientists-find-genetic-marker-carried-by-robert-the-bruce-s-relatives/ar-AATn4AD?cvid=1c34d7a25c0041fb88152d29bb42692f&ocid=winp1taskbar

robertmiles
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Message 2503 - Posted: 3 Feb 2022, 5:40:45 UTC

Rare gene variants may increase risk for severe NAFLD in obesity

https://www.healio.com/news/gastroenterology/20210916/rare-gene-variants-may-increase-risk-for-severe-nafld-in-obesity


Currently there’s no cure for rare types of cystic fibrosis, but researchers are making significant advances

https://horizon.scienceblog.com/1960/currently-theres-no-cure-for-rare-types-of-cystic-fibrosis-but-researchers-are-making-significant-advances/

robertmiles
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Message 2507 - Posted: 3 Feb 2022, 23:14:15 UTC

Educational outreach via direct messaging may improve FH screening, diagnosis

https://www.healio.com/news/cardiology/20210926/educational-outreach-via-direct-messaging-may-improve-fh-screening-diagnosis

robertmiles
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Message 2509 - Posted: 4 Feb 2022, 14:14:15 UTC

The genes behind the venom: New technique revolutionizes venom research

https://scienceblog.com/526746/the-genes-behind-the-venom-new-technique-revolutionizes-venom-research/


Illuminating Dark Matter in Human DNA

https://scienceblog.com/526637/illuminating-dark-matter-in-human-dna-2/

robertmiles
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Message 2510 - Posted: 4 Feb 2022, 16:05:37 UTC

CRISPR activation reveals “Rosetta Stone” of immune cell function

https://scienceblog.com/528118/crispr-activation-reveals-rosetta-stone-of-immune-cell-function/

robertmiles
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Message 2511 - Posted: 4 Feb 2022, 21:05:27 UTC

Targeted drug combo unprecedented against highly aggressive brain tumors

https://scienceblog.com/526877/targeted-drug-combo-unprecedented-against-highly-aggressive-brain-tumors/

robertmiles
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Message 2512 - Posted: 5 Feb 2022, 5:36:09 UTC

Brain Organoids Mimic Head Size Changes Associated with Type of Autism

https://scienceblog.com/524991/brain-organoids-mimic-head-size-changes-associated-with-type-of-autism/

robertmiles
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Message 2513 - Posted: 6 Feb 2022, 1:16:51 UTC

Massive Study Links Nearly 600 Genomic Regions to Self-Regulating Behaviors

https://scienceblog.com/525017/massive-study-links-nearly-600-genomic-regions-to-self-regulating-behaviors/


Genetic background can increase Hispanics risk for omega-3 deficiency

https://scienceblog.com/525091/genetic-background-can-increase-hispanics-risk-for-omega-3-deficiency/


The flower clock: How a small protein helps flowers to develop right and on time

https://scienceblog.com/525096/the-flower-clock-how-a-small-protein-helps-flowers-to-develop-right-and-on-time/

robertmiles
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Message 2514 - Posted: 6 Feb 2022, 16:44:06 UTC

Love long and prosper: Study finds genetic gems in Galápagos giant tortoise genomes

https://scienceblog.com/526745/live-long-and-prosper-study-examines-genetic-gems-in-galapagos-giant-tortoise-genomes/

robertmiles
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Message 2515 - Posted: 7 Feb 2022, 2:14:55 UTC

Neurobiologists identify a new gene important for healthy daily rhythms

https://scienceblog.com/526645/neurobiologists-identify-a-new-gene-important-for-healthy-daily-rhythms/


Illuminating Dark Matter in Human DNA

https://scienceblog.com/526617/illuminating-dark-matter-in-human-dna/

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