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De novo minibinders target SARS-CoV-2 Spike protein
https://www.bakerlab.org/index.php/2020/09/09/covid-minibinders/ |
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Pulling the plug on COVID-19
https://sciencenode.org/feature/Pulling%20the%20plug%20on%20coronavirus.php?clicked=readmore
ECCVID 2020: Lower plasma zinc levels associated with increased risk of death in COVID-19 patients
https://www.univadis.com/viewarticle/eccvid-2020-lower-plasma-zinc-levels-associated-with-increased-risk-of-death-in-covid-19-patients-099310b9-68de-323e-940f-17b5d9e56b47
The Potential Impact of Zinc Supplementation on COVID-19 Pathogenesis
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7365891/ |
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De novo design of picomolar SARS-CoV-2 miniprotein inhibitors
https://science.sciencemag.org/content/early/2020/09/08/science.abd9909 |
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Simple blood test predicts patients most likely to die from COVID-19
https://newatlas.com/health-wellbeing/coronavirus-blood-test-predicts-mortality-disease-severity-rdw/ |
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Could Zinc Help Fight COVID-19?
https://consumer.healthday.com/infectious-disease-information-21/coronavirus-1008/could-zinc-help-fight-covid-19-761488.html |
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Pandemic Provides New Target for Pain Relief Research
https://uahs.arizona.edu/tomorrow/pandemic-provides-new-target-pain-relief-research
Also related to COVID-19! |
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An Antioxidant Enzyme Therapeutic for COVIDâ€19
https://onlinelibrary.wiley.com/doi/10.1002/adma.202004901 |
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Another study suggests common cold protects some from COVID-19
https://www.upi.com/Health_News/2020/10/05/Another-study-suggests-common-cold-protects-some-from-COVID-19/3371601912308/
Lab tests suggest Israeli-made face mask eliminates over 99% of coronavirus
https://www.jpost.com/health-science/israeli-made-mask-eliminates-over-99-percent-of-coronavirus-lab-tests-suggest-644434?utm_source=taboola&utm_medium=referral&utm_campaign=JPost_99_US_PC&tblci=GiDgJyn9rezIcd9JrqPaoAbHY7CM7kRtByLdVqTywIvy4CDq3U8#tblciGiDgJyn9rezIcd9JrqPaoAbHY7CM7kRtByLdVqTywIvy4CDq3U8 |
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SARS-CoV-2 infection can block pain, opening up unexpected new possibilities for research into pain relief medication
https://theconversation.com/sars-cov-2-infection-can-block-pain-opening-up-unexpected-new-possibilities-for-research-into-pain-relief-medication-146280 |
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Studies offer new evidence for possible link between blood type and COVID-19 susceptibility
https://www.sciencedaily.com/releases/2020/10/201014161544.htm
The six strains of SARS-CoV-2
https://www.sciencedaily.com/releases/2020/08/200803105246.htm |
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A rare Covid-19 complication was reported in children. Now, it's showing up in adults.
https://www.nbcnews.com/health/health-news/rare-covid-19-complication-was-reported-children-now-it-s-n1243161?.tsrc=bell-brknews |
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The first time I've seen furin mentioned as related to COVID-19.
This names several antiviral medicine candidates.
An overview of COVID-19 with an emphasis on computational approach for its preventive intervention
https://link.springer.com/article/10.1007/s13205-020-02425-9?utm_campaign=SRBM_AWA_YM01_GL_13205_HP_TrendMDQ420
https://rdcu.be/b8MSl |
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"Ms Frederiksen cited a government report which said the mutated virus had been found to weaken the body's ability to form antibodies, potentially making the current vaccines under development for Covid-19 ineffective."
https://www.bbc.com/news/world-europe-54818615
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English study suggests T cells could be sufficient to protect from COVID-19
https://www.reuters.com/article/us-health-coronavirus-britain-tcell/english-study-suggests-t-cells-could-be-sufficient-to-protect-from-covid-19-idUSKBN27Q004 |
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"Ms Frederiksen cited a government report which said the mutated virus had been found to weaken the body's ability to form antibodies, potentially making the current vaccines under development for Covid-19 ineffective."
https://www.bbc.com/news/world-europe-54818615
I've seen an article saying that a new gene in the virus, overlapping with a known gene, is responsible for that. Not easily seen without a paid subscription, though. |
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valtercProject administrator Project tester Send message
Joined: 30 Oct 13 Posts: 624 Credit: 34,677,535 RAC: 0
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"Ms Frederiksen cited a government report which said the mutated virus had been found to weaken the body's ability to form antibodies, potentially making the current vaccines under development for Covid-19 ineffective."
https://www.bbc.com/news/world-europe-54818615
I've seen an article saying that a new gene in the virus, overlapping with a known gene, is responsible for that. Not easily seen without a paid subscription, though.
There is a reddit about this (minks mutation) https://www.reddit.com/r/COVID19/comments/jrl0f1/working_paper_on_sarscov2_spike_mutations_arising/ |
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In an international study in Science, 10 percent of nearly 1,000 Covid-19 patients who developed life-threatening pneumonia had antibodies that disable key immune system proteins called interferons. These antibodies — known as autoantibodies, because they attack the body itself — weren't found at all in 663 people with mild or asymptomatic Covid-19 infections. Only four of 1,227 healthy patients had the autoantibodies. The study was led by the Covid Human Genetic Effort, which includes 200 research centers in 40 countries.
"This is one of the most important things we've learned about the immune system since the start of the pandemic," said Dr. Eric Topol, executive vice president for research at Scripps Research in San Diego, who wasn't involved in the new study. "This is a breakthrough finding."
In a second Science study by the same team, the authors found that an additional 3.5 percent of critically ill patients had mutations in genes that control the interferons involved in fighting viruses. Given that the body has 500 to 600 of those genes, it's possible that researchers will find more mutations, said Qian Zhang, lead author of the second study.
https://news.yahoo.com/why-covid-19-kills-certain-100211975.html |
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The MMR vaccine offer some protection against COVID-19.
Analysis of Measles-Mumps-Rubella (MMR) Titers of Recovered COVID-19 Patients
https://mbio.asm.org/content/11/6/e02628-20 |
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The Mystery Of India's Plummeting COVID-19 Cases
https://www.npr.org/sections/goatsandsoda/2021/02/01/962821038/the-mystery-of-indias-plummeting-covid-19-cases |
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Have you expanded all the genes for the 332 proteins listed in these pan-coronaviral interactomes???
Comparative host-coronavirus protein interaction networks reveal pan-viral disease mechanisms
https://science.sciencemag.org/content/370/6521/eabe9403?ijkey=4c0e55f7dd6406f86b89b81afbe322ff8df667a6&keytype2=tf_ipsecsha
A SARS-CoV-2 protein interaction map reveals targets for drug repurposing
https://pubmed.ncbi.nlm.nih.gov/32353859/
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