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robertmiles
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Message 1957 - Posted: 19 Sep 2020, 3:58:21 UTC

De novo minibinders target SARS-CoV-2 Spike protein

https://www.bakerlab.org/index.php/2020/09/09/covid-minibinders/

robertmiles
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Message 1958 - Posted: 25 Sep 2020, 12:55:56 UTC

Pulling the plug on COVID-19

https://sciencenode.org/feature/Pulling%20the%20plug%20on%20coronavirus.php?clicked=readmore


ECCVID 2020: Lower plasma zinc levels associated with increased risk of death in COVID-19 patients

https://www.univadis.com/viewarticle/eccvid-2020-lower-plasma-zinc-levels-associated-with-increased-risk-of-death-in-covid-19-patients-099310b9-68de-323e-940f-17b5d9e56b47


The Potential Impact of Zinc Supplementation on COVID-19 Pathogenesis

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7365891/

robertmiles
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Message 1959 - Posted: 25 Sep 2020, 19:24:09 UTC

De novo design of picomolar SARS-CoV-2 miniprotein inhibitors

https://science.sciencemag.org/content/early/2020/09/08/science.abd9909

robertmiles
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Message 1960 - Posted: 26 Sep 2020, 22:45:31 UTC

Simple blood test predicts patients most likely to die from COVID-19

https://newatlas.com/health-wellbeing/coronavirus-blood-test-predicts-mortality-disease-severity-rdw/

robertmiles
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Message 1977 - Posted: 1 Oct 2020, 3:57:12 UTC

Could Zinc Help Fight COVID-19?

https://consumer.healthday.com/infectious-disease-information-21/coronavirus-1008/could-zinc-help-fight-covid-19-761488.html

robertmiles
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Message 1980 - Posted: 5 Oct 2020, 23:47:19 UTC

Pandemic Provides New Target for Pain Relief Research

https://uahs.arizona.edu/tomorrow/pandemic-provides-new-target-pain-relief-research

Also related to COVID-19!

robertmiles
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Message 1981 - Posted: 6 Oct 2020, 3:06:36 UTC

An Antioxidant Enzyme Therapeutic for COVID‐19

https://onlinelibrary.wiley.com/doi/10.1002/adma.202004901

robertmiles
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Message 1984 - Posted: 8 Oct 2020, 0:35:07 UTC

Another study suggests common cold protects some from COVID-19

https://www.upi.com/Health_News/2020/10/05/Another-study-suggests-common-cold-protects-some-from-COVID-19/3371601912308/


Lab tests suggest Israeli-made face mask eliminates over 99% of coronavirus

https://www.jpost.com/health-science/israeli-made-mask-eliminates-over-99-percent-of-coronavirus-lab-tests-suggest-644434?utm_source=taboola&utm_medium=referral&utm_campaign=JPost_99_US_PC&tblci=GiDgJyn9rezIcd9JrqPaoAbHY7CM7kRtByLdVqTywIvy4CDq3U8#tblciGiDgJyn9rezIcd9JrqPaoAbHY7CM7kRtByLdVqTywIvy4CDq3U8

robertmiles
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Message 1999 - Posted: 12 Oct 2020, 1:26:13 UTC

SARS-CoV-2 infection can block pain, opening up unexpected new possibilities for research into pain relief medication

https://theconversation.com/sars-cov-2-infection-can-block-pain-opening-up-unexpected-new-possibilities-for-research-into-pain-relief-medication-146280

robertmiles
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Message 2013 - Posted: 17 Oct 2020, 3:23:24 UTC

Studies offer new evidence for possible link between blood type and COVID-19 susceptibility

https://www.sciencedaily.com/releases/2020/10/201014161544.htm


The six strains of SARS-CoV-2

https://www.sciencedaily.com/releases/2020/08/200803105246.htm

robertmiles
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Message 2016 - Posted: 18 Oct 2020, 1:35:51 UTC

A rare Covid-19 complication was reported in children. Now, it's showing up in adults.

https://www.nbcnews.com/health/health-news/rare-covid-19-complication-was-reported-children-now-it-s-n1243161?.tsrc=bell-brknews

robertmiles
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Message 2023 - Posted: 21 Oct 2020, 0:24:58 UTC

The first time I've seen furin mentioned as related to COVID-19.

This names several antiviral medicine candidates.

An overview of COVID-19 with an emphasis on computational approach for its preventive intervention

https://link.springer.com/article/10.1007/s13205-020-02425-9?utm_campaign=SRBM_AWA_YM01_GL_13205_HP_TrendMDQ420

https://rdcu.be/b8MSl

Falconet
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Message 2061 - Posted: 5 Nov 2020, 21:17:19 UTC
Last modified: 5 Nov 2020, 21:19:19 UTC

"Ms Frederiksen cited a government report which said the mutated virus had been found to weaken the body's ability to form antibodies, potentially making the current vaccines under development for Covid-19 ineffective."

https://www.bbc.com/news/world-europe-54818615
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robertmiles
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Message 2065 - Posted: 11 Nov 2020, 1:19:47 UTC

English study suggests T cells could be sufficient to protect from COVID-19

https://www.reuters.com/article/us-health-coronavirus-britain-tcell/english-study-suggests-t-cells-could-be-sufficient-to-protect-from-covid-19-idUSKBN27Q004

robertmiles
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Message 2066 - Posted: 11 Nov 2020, 1:24:24 UTC - in response to Message 2061.

"Ms Frederiksen cited a government report which said the mutated virus had been found to weaken the body's ability to form antibodies, potentially making the current vaccines under development for Covid-19 ineffective."

https://www.bbc.com/news/world-europe-54818615

I've seen an article saying that a new gene in the virus, overlapping with a known gene, is responsible for that. Not easily seen without a paid subscription, though.

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Message 2068 - Posted: 11 Nov 2020, 11:35:53 UTC - in response to Message 2066.
Last modified: 11 Nov 2020, 11:37:08 UTC

"Ms Frederiksen cited a government report which said the mutated virus had been found to weaken the body's ability to form antibodies, potentially making the current vaccines under development for Covid-19 ineffective."

https://www.bbc.com/news/world-europe-54818615

I've seen an article saying that a new gene in the virus, overlapping with a known gene, is responsible for that. Not easily seen without a paid subscription, though.

There is a reddit about this (minks mutation) https://www.reddit.com/r/COVID19/comments/jrl0f1/working_paper_on_sarscov2_spike_mutations_arising/

Jim1348
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Message 2073 - Posted: 13 Nov 2020, 22:55:58 UTC

In an international study in Science, 10 percent of nearly 1,000 Covid-19 patients who developed life-threatening pneumonia had antibodies that disable key immune system proteins called interferons. These antibodies — known as autoantibodies, because they attack the body itself — weren't found at all in 663 people with mild or asymptomatic Covid-19 infections. Only four of 1,227 healthy patients had the autoantibodies. The study was led by the Covid Human Genetic Effort, which includes 200 research centers in 40 countries.

"This is one of the most important things we've learned about the immune system since the start of the pandemic," said Dr. Eric Topol, executive vice president for research at Scripps Research in San Diego, who wasn't involved in the new study. "This is a breakthrough finding."

In a second Science study by the same team, the authors found that an additional 3.5 percent of critically ill patients had mutations in genes that control the interferons involved in fighting viruses. Given that the body has 500 to 600 of those genes, it's possible that researchers will find more mutations, said Qian Zhang, lead author of the second study.

https://news.yahoo.com/why-covid-19-kills-certain-100211975.html

robertmiles
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Message 2179 - Posted: 26 Jan 2021, 23:48:19 UTC

The MMR vaccine offer some protection against COVID-19.

Analysis of Measles-Mumps-Rubella (MMR) Titers of Recovered COVID-19 Patients

https://mbio.asm.org/content/11/6/e02628-20

robertmiles
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Message 2191 - Posted: 2 Feb 2021, 21:42:38 UTC

The Mystery Of India's Plummeting COVID-19 Cases

https://www.npr.org/sections/goatsandsoda/2021/02/01/962821038/the-mystery-of-indias-plummeting-covid-19-cases

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Message 2194 - Posted: 3 Feb 2021, 21:05:58 UTC
Last modified: 3 Feb 2021, 21:09:55 UTC

Have you expanded all the genes for the 332 proteins listed in these pan-coronaviral interactomes???

Comparative host-coronavirus protein interaction networks reveal pan-viral disease mechanisms
https://science.sciencemag.org/content/370/6521/eabe9403?ijkey=4c0e55f7dd6406f86b89b81afbe322ff8df667a6&keytype2=tf_ipsecsha


A SARS-CoV-2 protein interaction map reveals targets for drug repurposing
https://pubmed.ncbi.nlm.nih.gov/32353859/
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